AssayLink

Template catalogue

Every assay definition, including drafts and templates under review.

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Assay type

✓ cocktail inhibition assay2clearance assay1hepatocyte induction assay1

Experimental setting

in vitro4

Assay format

cell-based4

Detection type

UPLC-MS/MS4qPCR1

Target

CYP1A23CYP3A43CYP1A12CYP2C192CYP2C82CYP2C92CYP2D62

Expected readout

AUCR2CLint1Emax1Fmax1fold induction1NOEL1t1/21

2 templates matching your filters

ADME / DMPK

Metabolism, clearance, drug–drug interaction, permeability, transport and protein binding.

2
  • PK In Vitro Stability (imported)

    PK-IVS · v1 · Dr Amelia Ostrowski

    Draft

    Assessment of CYP inhibition potential and DDI risk for a test compound by quantifying reversible and time-dependent (mechanism-based) inhibition across major CYP isoforms; reporting AUCR metrics and inhibition strength categories.

    cocktail inhibition assayCYP1A1CYP1A2CYP2C8CYP2C9UPLC-MS/MSAUCR+3 targets
  • PK CIA

    PK-CIA · v1 · Dr Amelia Ostrowski

    Published

    Assessment of CYP inhibition potential and DDI risk for a test compound by quantifying reversible and time-dependent (mechanism-based) inhibition across major CYP isoforms; reporting AUCR metrics and inhibition strength categories.

    cocktail inhibition assayCYP1A1CYP1A2CYP2C8CYP2C9UPLC-MS/MSAUCR+3 targets